Available clinical trials in the UNC Department of Pediatrics vary by division, specialty or center. Additional information about clinical trials and their availability may be found by visiting Research for Me, which is administered by the North Carolina Translational and Clinical Sciences Institute (NCTraCS), or ClinicalTrials.gov. For divisions with active or ongoing clinical trials, experienced research teams include both clinicians and coordinators who specialize in care and management of pediatric populations impacted by common or rare diseases.

It is important to note that while some clinical trials are open and enrolling, others are closed or maintain waitlists for prospective participants. Also, some clinical trials are administered by faculty from the Department of Pediatrics, but only recruit adults.

Area of StudyStudy TitleTarget AgeContact Information
Adolescent Health and Well-BeingCognition and Neuroimaging in TeensElementary, TeenHannah Waltz
919-843-9671
Adolescent Health and Well-BeingiTBS for AdolescentsTeenElizabeth Pugliese
984-974-3843
AlopeciaAlopecia Areata Research Study 1032Teen, AdultSuzy Caballero
984-974-3682
AllergiesHouse Dust Mite StudyElementaryMiriam Davis
919-966-2333
AllergiesOmalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants (OUtMATCH)Preschool, Elementary, Teen, AdultSarah Bennick
919-962-4409
Lauren Herlihy
919-962-4406
AllergiesSafety and Efficacy Study of Viaskin Peanut in Peanut-allergic Young Children 1-3 Years of Age (EPITOPE)PreschoolDeanna Hamilton
919-259-4729
AsthmaORBEXInfant, PreschoolMiriam Davis
919-966-2333
orbex@unc.edu
AsthmaUNC Asthma Registry for KidsInfant, Preschool, Elementary, Teen, AdultMiriam Davis
919-966-2333
Attention-Deficit Hyperactivity DisorderBrain Maturation Across Puberty in ADHD (BrainMAP)ElementaryAlexa Monachino
919-843-3753
Autoimmune DiseasesBenralizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA)AdultTeresa Dickson
919-962-8241
Autoimmune DiseasesCARRA RegistryInfant, Preschool, Elementary, Teen, AdultTeresa Dickson
919-962-8241
Autoimmune DiseasesLimit JIAPreschool, Elementary, TeenTeresa Dickson
919-962-8241
Bones, Joints and MusclesACL Reconstruction and Biofeedback StudyTeen, AdultAnne Wandishin
703-869-5572
Bones, Joints and MusclesSimple Bone Cysts in Kids (SBoCK)Preschool, Elementary, Teen, AdultJulie Titter
919-966-5495
CancerAdministration of Autologous CAR-T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch in Patient with Acute Lymphoblastic LeukemiaPreschool, Elementary, Teen, AdultCatherine Cheng
Spencer Laing
919-445-4208
CancerAdministration of T Lymphocytes for Prevention of Relapse of LymphomasPreschool, Elementary, Teen, AdultCatherine Cheng
Spencer Laing
919-445-4208
CancerCabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare TumorsPreschool, Elementary, Teen, AdultJuanita Ramirez
877-668-0683
CancerImmunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK CellsInfant, Preschool, Elementary, Teen, AdultJuanita Ramirez
877-668-0683
CancerMIBG With DinutuximabPreschool, Elementary, Teen, AdultJuanita Ramirez
877-668-0683
CancerNab-Paclitaxel and Gemcitabine for Recurrent/Refractory SarcomaElementary, Teen, AdultJuanita Cuffee
919-843-7025
CancerStudy of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory NeuroblastomaPreschool, Elementary, Teen, AdultCatherine Cheng
Spencer Laing
919-445-4208
CancerStudy of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHLPreschool, Elementary, Teen, AdultCatherine Cheng
Spencer Laing
919-445-4208
CancerStudy of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous LineagePreschool, Elementary, Teen, AdultJuanita Ramirez
877-668-0683
Cerebral PalsyHand Function in Children with Cerebral PalsyElementary, TeenJames McCall
336-480-8914
COVID-19Survey on Psychological Experiences during COVID-19Teen, AdultHeidi Ojalehto
ojalehto@unc.edu
Cystic FibrosisInitial and Chronic Methicillin Resistant Staphylococcus Aureus (MRSA) Infection in Cystic Fibrosis (CF) (TRI-STAR)Preschool, Elementary, Teen, AdultColin O'Leary
919-966-1055
Developmental DisordersRegistry for Autism, Fragile X Syndrome, and Intellectual and Developmental DisabilitiesInfant, Preschool, Elementary, Teen, AdultRenee Clark
919-966-5232
DiabetesDINAMO Type 2 Diabetes StudyElementary, TeenMiriam Davis
919-966-2333
DiabetesPROTECT StudyElementary, Teen, AdultMiriam Davis
919-966-2333
DiabetesTrialNet Pathway to Prevention StudyPreschool, Elementary, Teen, AdultMiriam Davis
919-966-2333
E-Cigarettes, Tobacco and VapingIn-vivo effects of E-cigarette aerosolAdultBrian Ring
919-843-8472
E-Cigarettes, Tobacco and VapingStudy on Internet Tobacco Sales to YouthTeenJean Phillips-Weiner
ITVStudy@unc.edu
Eating DisordersMicrobiome-mediated Weight, Anxiety, and Stress Dysregulation in Anorexia Nervosa (Microbiome)Teen, AdultQuyen Tang
919-966-8231
EczemaBleach vs. Bubbles: Assessing the Impact of the Bathroom Environment on EczemaInfant, Preschool, Elementary, TeenCraig Burkhart
984-974-3900
Eosinophilic EsophagitisEosinophilic Esophagitis (EoE) StudyTeen, AdultZack Park
919-966-2996
Eosinophilic EsophagitisEosinophilic Esophagitis StudyTeen, Adult Sean LaFata
919-843-7684
Eosinophilic EsophagitisMepolizumab for EoE StudyTeen, AdultNicole Allen
919-966-8559
Eosinophilic EsophagitisTesting a New Drug to Treat Eosinophilic EsophagitisElementary, Teen, AdultNicole Gniewek
919-843-0688
GenomicsNorth Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 (NCGENES2)Infant, Preschool, Elementary, Teen, AdultJeanette Benson
919-843-1017
Hearing LossPediatric Expanded Cochlear Implant Indications (PECII)Infant, PreschoolLisa Park
919-419-1449
HIVAllyQuestTeen, AdultKelly Knudtson
919-962-4640
HIVCOMPARE: Apps to increase HIV testing and PrEP uptakeTeen, AdultCasey Horvitz
919-445-3802
HIVP3 (Prepared, Protected, emPowered): Testing an App to Improve PrEP AdherenceTeen, AdultKelly Knudtson
p3@med.unc.edu
HIVYouTHrive - Connecting youth and young adults to optimize ART adherenceTeen, AdultCasey Horvitz
919-445-3802
Inflammatory Bowel DiseaseIBD Partners Kids & TeensInfant, Preschool, Elementary, TeenLaura Weisbein
919-843-7828
Inflammatory Bowel DiseaseLow Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy (COMBINE)Elementary, Teen, AdultMary Lewis
919-843-9547
Inflammatory Bowel DiseaseThe Pediatric IBD Network Improvement CollaborativePreschool, Elementary, Teen, AdultParis Bennett
paris_bennett@med.unc.edu
Kidney DiseaseCureGN (Cure Glomerulonephropathy)Infant, Preschool, Elementary, Teen, AdultMaggie D'Angelo
919-619-1773
Kidney DiseaseDUPLEX : study of Sparsentan for FSGSElementary, Teen, AdultAnne Froment
919-445-2622
Kidney DiseaseGDCN RegistryInfant, Preschool, Elementary, Teen, AdultKristin Brock
919-445-2623
Kidney DiseaseLIPOSORBER LA-15 system for Adult and Pediatric FSGSElementary, Teen, AdultAnne Froment
919-445-2622
LiverFructose-Liver Fat studyElementary, Teen, AdultBrea Nance
704-250-5055
Liver A Prospective, Observational, Non-Interventional, Post-Marketing, Patient Registry to Collect Data on Routine Clinical Care in Patients Treated with Cholbam®/Kolbam® (Cholic Acid)Infant, Preschool, Elementary, TeenParis Bennett
paris_bennett@med.unc.edu
Medication and Vaccine EfficacyApnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood VaccinesInfantJennifer Talbert
984-974-7865
jtalbert@med.unc.edu
Medication and Vaccine EfficacyGSK V72_57: Safety and Immunogenicity of GSK Meningococcal Group B vaccine and 13-valent Pneumococcal Vaccine administered with routine vaccinesInfantJudy Mulvihill
984-444-7967
Medication and Vaccine EfficacyPharmacokinetics and Safety of Drugs in Lactating Women and Breastfed InfantsInfant, Teen, AdultJennifer Talbert
984-974-7865
jtalbert@med.unc.edu
Medication and Vaccine EfficacyPharmacokinetics of Off Label Pediatric MedicationsInfant, Preschool, ElementaryJennifer Talbert
984-974-7865
jtalbert@med.unc.edu
Medication and Vaccine EfficacySafety of Sildenafil in Premature Infants (SIL02)InfantJennifer Talbert
984-974-7865
jtalbert@med.unc.edu
Mental Health1289-0032 Research StudyTeen, AdultJennifer Nieri
877-774-6319
Multiple SclerosisRelapsing Remitting Multiple Sclerosis Study for Pediatric Persons aged 10-17 years oldElementary, Teen, AdultPatricia Orozco
919-966-5039
NeurodevelopmentBaby Connectome ProjectInfant, PreschoolTaylor Potts
919-843-7943
NeurodevelopmentIMPACT Imaging Study for ChildrenInfant, AdultSarah Jarvis
sarah_jarvis@med.unc.edu
NeurodevelopmentPediatric Brain Imaging StudyInfant, PreschoolAnne Moran
anne_moran@med.unc.edu
NeurodevelopmentWellness Health and Life Experiences StudyPreschool, ElementaryKinjal Patel
whalestudy@unc.edu
NutritionBrain Imaging, eye Tracking, and Eating Study (BITES)ElementaryGrace Shearrer
BITEStudy@unc.edu
ObesityUNC Nutritional Research Institute Children Health StudyElementary, Teen, AdultBrea Nance
704-250-5055
OphthalmologyCerebrotendinous Xanthomatosis (CTX) Prevalence StudyPreschool, Elementary, Teen, AdultElizabeth DuBose
919-260-1422
Sickle Cell DiseaseBone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) Teen, AdultKimberly Kasow
919-966-1178
Sickle Cell DiseaseEarly Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell TransplantationPreschool, ElementaryKimberly Kasow
919-966-1178
Sickle Cell DiseaseSTRIDE BiorepositoryTeen, AdultKimberly Kasow
919-966-1178
Speech Perception and Auditory ResponseStudy of Speech Perception in ChildrenPreschool, Elementary, Teen, AdultDiana Regalado
919-962-7089
Speech, Dentofacial AbnormalitiesOrthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses (OSP)Teen, AdultSherrill Phillips
sherrill_phillips@unc.edu