Cancer and Blood Disorders
About Our Research
Research efforts within the Division of Hematology-Oncology include projects involving: bleeding and clotting disorders, childhood cancers, hemophilia A, hemophilia B, sickle cell disease, leukemia, lymphoma, health disparities, solid tumors, bone marrow transplant, hematopoietic stem cell transplant, long-term effects of cancer treatments, T-cell therapy, supportive care to survivors of childhood cancer, and many more.
Our faculty collaborates in these projects with colleagues across campus, including researchers working throughout the School of Medicine, Lineberger Comprehensive Cancer Center, the Gillings School of Global Public Health, and the Eshelman School of Pharmacy. The division is also a member of the Children’s Oncology Group, a national consortium of pediatric cancer centers.
Ongoing Clinical Trials and Studies
- A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
- Administration of Autologous CAR-T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch in Patient with Acute Lymphoblastic Leukemia
- Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
- UNC Childhood, Adolescent, and Young Adult Cancer Registry
- Expanded Access Protocol Using 131I-MIBG
- Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
- Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL
- Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma
- Understanding Outcome Differences in Adolescents and Young Adults with Acute Lymphoblastic Leukemia (ALL)
- Improve Adherence to Childhood Cancer Survivorship
- Pediatric Oncology Tissue to Support Further Research
Our Researchers
