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Division of Endocrinology & Metabolism

Obesity is a serious disease which can cause or worsen approximately 200 other medical conditions. Apart from the impact on health, individuals suffering from obesity have a significantly worsened quality of life due to the physical limitations imposed by their weight on a day to day basis.

We at the UNC Medical Weight Program understand the medical, physical and social burden that obesity places on an individual and have created a supportive environment to provide modern treatments based on scientific study and understanding of obesity. Our comprehensive medical obesity treatment services are designed to improve patient health and quality of life by concentrating on long term sustained weight loss outcomes. We specialize in treating medically complex patients with serious medical illnesses, who benefit from management of their obesity.

Our Programs

Contrary to common belief, obesity is a very complex disease with numerous causes that go well beyond eating more and exercising less. Due to the complex etiology, multiple strategies are necessary for effective treatment and long term management. Furthermore the responses of individuals to treatments are variable. We therefore offer a range of treatments in a step wise strategy to encompass responses from different individuals with unique medical goals.

The services offered include:

A comprehensive evaluation to identify possible causes for the obesity, undiagnosed medical illnesses due to obesity, barriers to treatment. Based on the comprehensive evaluation, the medical provider determines the best treatment options, which are then discussed with patients in detail to formulate the final treatment and follow up plan.

Examples of the treatment options are:

  • Dietary modifications by working individually or in groups with a dietitian.
  • Additional lifestyle interventions directed by the medical provider or referral to specialized providers as necessary.
  • Medication adjustments to reduce exposure to weight gain causing medications.
  • Addition of medications to help bring about fat loss safely.
  • Referral for effective endoscopic procedures to help with obesity treatment.

In addition to the standard long term weight management programs to promote weight loss and maintenance, we offer a short term Optifast program utilizing balanced very low calorie meal replacements to achieve substantial fat loss in preparation for medical or surgical procedures.

We work closely with the bariatric surgery team to have their services available for patients as needed.

Provider Team

Sriram Machineni, MDSriram Machineni, MDCC 2020 Top Doctor Logo
Director, UNC Medical Weight Program

Dr. Machineni is Assistant Professor of Medicine at UNC and has been a diplomate of the American Board of Obesity Medicine since its inception in 2012. He completed a clinical and research fellowship in Obesity Medicine from Massachusetts General Hospital and Harvard Medical School. After completion of his fellowship, he served as an Instructor at Harvard Medical School and faculty member at the MGH Weight Center in Boston. His research interests are geared towards understanding the way the human body regulates its weight. He is presently involved in research studying personalized medicine strategies for obesity. To date, Dr. Machineni is the only physician with a Castle Connolly distinction for obesity medicine in the Triangle area.


Shannon E. Aymes, MD, MPH
Obesity Medicine Physician

Dr. Aymes is Assistant Professor of Medicine in the Division of Endocrinology and Metabolism. She completed an internal medicine residency at the Robert Wood Johnson University Hospital (Rutgers), and training in preventative medicine and clinical obesity medicine at UNC. Her clinical and research interests include weight management, population health, and health policy. Her philosophy for weight management includes addressing many of the causes of weight gain including lifestyle, stress, nutrition, exercise, sleep, and medications.

Melissa Cranford, RDN, LDNMelissa Cranford, RDN, LDN

After completing her undergraduate degree in dietetic and nutrition, Melissa started her career as an inpatient dietitian in South Florida working in critical care units and with patients post bariatric surgery. In her present role at the UNC Medical Weight Program she focuses on nutritional management of chronic diseases and obesity. She is a member of the Academy of Dietetics and Nutrition and The Obesity Society. Melissa is contagiously positive, and passionate about nutrition and healthy living! Her comprehensive approach encompasses physical, mental and spiritual wellbeing. Melissa believes in providing sound professional advice and practical ideas to simplify nutrition.

Natasha Rosser, PA-CNatasha Rosser, PA-C

Natasha completed her Physician Assistant Studies at George Washington University in 2010 and a has a Masters of Science in Health Sciences. Since graduating, she has worked in primary care until joining The UNC Weight Clinic in September 2019. Natasha enjoys focusing on the whole patient and exploring the many factors influencing their health. She is passionate about working with patients to improve their health and quality of life.

Margaret (Peggy) Wrobleski, PhD, RDN, LDNMargaret (Peggy) Wrobleski, PhD, RDN, LDN

Dr. Wrobleski is a Registered Dietitian with extensive experience in the field of weight management. She was a weight management counselor early in her career and facilitated weight loss groups while working as the Bionutrition Research Dietitian at Johns Hopkins Bayview Medical Center. Dr. Wrobleski collaborated on childhood and adolescent obesity prevention research at the University of Maryland in Baltimore and served as the Program Manager of the Johns Hopkins Weight Management Center.

Dr. Wrobleski is happy to be back home in North Carolina and working in the UNC Multidisciplinary Weight Management Program. She finds counseling patients to be very rewarding work, and enjoys helping patients achieve weight loss success through a customized, personal approach to weight loss.

UNC Medical Weight Program in the News


What to do if you would like to be seen in the UNC Medical Weight program

Welcome! You have taken the first step in familiarizing yourself with our program.

  • You will need to contact your primary care physician to get a referral to the program.
  • After we receive the referral from your medical provider, we will call you to set up your appointment. You will complete a brief medical questionnaire at the time of scheduling in preparation for your appointment.

If you have questions, please call the UNC Diabetes & Endocrinology Clinic at Eastowne at 984-974-2950.

Instructions for Referring Providers