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UNC Researchers Publish Groundbreaking Protocol for Combining Brain Imaging and Electrochemical Recording

October 23, 2025
Chapel Hill, N.C. — A team at the UNC Center for Animal Magnetic Resonance Imaging (CAMRI) has published a pioneering protocol that outlines how to integrate electrochemical brain recordings with MRI imaging—a breakthrough that could transform neuroscience research and clinical applications. CAMRI is part of BRIC’s service core and provides...

Prospective Data Collection for DBS Outcomes Prediction

October 14, 2025
We are using specialized functional MRI for people receiving deep brain stimulation surgery to help predict who will benefit most from this procedure.

Biomarkers in the Brain Optimization in Severe Traumatic Brain Injury Trial (Bio-BOOST)

October 14, 2025
BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury. Detailed Description Traumatic brain injury (TBI) remains a major cause of death and disability, with an estimated cost of $45 billion/year in the...

Parkinson’s Disease Genetics Registry

October 14, 2025
This is a genetic registry study aimed at developing a central location to store Parkinson’s Disease genetic data for future research use.

ARGX-113-2006

October 14, 2025
Open-label Uncontrolled Trial to Evaluate Pharmacokinetics, Pharmacodynamics, Safety, and Activity of Efgartigimod in Children From 2 to Less Than 18 Years of Age With Generalized Myasthenia Gravis- ARGX-113-2006. For more information or to register for the study, contact Study Coordinator Manisha Chopra

Novartis SOSTOS

October 14, 2025
This study aims to investigate whether multiple sclerosis patients who haven’t had a relapse within the past year would benefit from switching to ofatumumab VS. continuing their current therapy, based on measures of disease activity, and a baseline neurofilament light level. Neurofilament is a marker of nerve cell loss in...

Duke/UNC ADRC Memory & Aging Study

October 14, 2025
The Memory & Aging Study by the Duke-UNC Alzheimer’s Disease Research Center aim is to pinpoint the biological factors related to both regular brain aging and diseased brain decline. This study works with a large group of younger and older adults, with and without memory problems.

CorEvitas SPHERES Registry for Neuromyelitis Optica Spectrum Disorder (NMOSD)

October 14, 2025
The objective of the registry is to create a cohort of patients with NMOSD. This registry will be used for future research, as well as improvements to the diagnosis, treatment, and understanding of NMOSD.

DRPLA Natural History and Biomarkers Study

October 14, 2025
The purpose of this study is to characterize the natural history of DRPLA patients using a variety of clinical and biomarker modalities and to identify genetic factors, biomarkers, and clinical measures that could predict disease progression.

Genetic Determinants of Neurological and Developmental Disorders

October 13, 2025
The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.