Category: Clinical Trial Listing

This is a genetic registry study aimed at developing a central location to store Parkinson’s Disease genetic data for future research use.

Open-label Uncontrolled Trial to Evaluate Pharmacokinetics, Pharmacodynamics, Safety, and Activity of Efgartigimod in Children From 2 to Less Than 18 Years of Age With Generalized Myasthenia Gravis- ARGX-113-2006. For more information or to register for the study, contact Study Coordinator Manisha Chopra

This study aims to investigate whether multiple sclerosis patients who haven’t had a relapse within the past year would benefit from switching to ofatumumab VS. continuing their current therapy, based on measures of disease activity, and a baseline neurofilament light level. Neurofilament is a marker of nerve cell loss in...

The Memory & Aging Study by the Duke-UNC Alzheimer’s Disease Research Center aim is to pinpoint the biological factors related to both regular brain aging and diseased brain decline. This study works with a large group of younger and older adults, with and without memory problems.

The objective of the registry is to create a cohort of patients with NMOSD. This registry will be used for future research, as well as improvements to the diagnosis, treatment, and understanding of NMOSD.

The purpose of this study is to characterize the natural history of DRPLA patients using a variety of clinical and biomarker modalities and to identify genetic factors, biomarkers, and clinical measures that could predict disease progression.

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

The purpose of the study is to identify certain processes following brain injury that may be associated with the risk of developing epilepsy.

Brief Summary Long-term, multicenter, multinational, observational, registry of patients with gMG that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT) such as eculizumab (Soliris®) and ravulizumab (Ultomiris®). Detailed Description At the time of enrollment in the Registry, participant records will...

This is a study being conducted at many sites across the US to evaluate patients who are older than 50 years old, who have sudden bleeding in the brain (intracerebral hemorrhage) while taking a statin medication. It is unclear if continuing to take a statin medication after this type of...