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ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

October 10, 2025
The purpose of this study is to evaluate both sporadic (not inherited), and familial (inherited), forms of frontotemporal lobar degeneration (FTLD). Patients include both those who have symptoms of FTLD and those who do not (yet have a family history involving FTLD). This is an observational study, meaning that there...

Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery (ASPIRE)

October 10, 2025
The ASPIRE trial aims to study anticoagulant medications in patients who have had an intracerebral hemorrhage (bleeding in the brain) who also have atrial fibrillation (irregular heartbeats). Participants who agree to study participation will receive either Aspirin or Apixaban and followed for 12-36 months to see if they have any...

Brain Oxygen Optimization in Severe Traumatic Brain Injury-Phase 3 (BOOST-3)

October 10, 2025
A multicenter, randomized, blinded-endpoint, comparative effectiveness study of goal-directed critical care based upon monitoring of brain tissue oxygen and intracranial pressure versus monitoring of intracranial pressure alone in patients with severe traumatic brain injury. Overview Traumatic brain injury (TBI) is a major cause of death and disability in developed societies....

Dementia with Lewy Bodies Consortium (DLBC)

October 10, 2025
This study aims to establish a research network and registry for persons with Dementia with Lewy Bodies (DLB) in order to characterize the disease and aid in future clinical trials.