September 17, 2024
Yohei Hisada, Ph.D. was awarded an R56 from the NIH NHLBI in the amount of $764,817 for a one-year project titled “Mechanisms of Coagulopathy and Bleeding in Acute Promyelocytic Leukemia.” The award will fund studies to evaluate the hemorrhagic phenotype associated with hyperfibrinolysis in acute promyelocytic leukemia (APL), as well as the global changes in …
September 16, 2024
Nigel Key, MD was an invited plenary speaker at the French Congress on Hemostasis 2024 on September 12 in Lille, France. The title of his lecture was “Is tranexamic acid a universal hemostatic agent? What is left to learn about mechanism, dosing, timing, risks?” Website: https://www.congres-hemostase.com/
September 10, 2024
Abby Kordeliski has had the final version of her paper “4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model” published in Blood along with the cover image. Abby works in the Wolfgang Bergmeier laboratory in Mary Ellen Jones Building, Congratulations Abby! Cover image Link to the article that …
September 3, 2024
On August 23, 2024, we hosted our first seminar speaker of the Fall 2024 Semester, Dr. Mary Cushman from the University of Vermont. Dr. Cushman is the 2024 BRC Trainee Invited Speaker and her visit included a fantastic interactive workshop on how to write a research article, “Dialogue with a Recovering Editor” and a seminar …
August 20, 2024
Steven Grover, PhD has been awarded an R01 from NIH NHLBI in the amount of $3,275,000 for a five-year project titled “Regulation of Coagulation and Thrombosis by C1-inhibitor”. The award will fund translational studies to evaluate the procoagulant phenotype associated with congenital C1-inhibitor deficiency and the potential utility of FDA approved C1-inhibitor preparations as hemostasis …
August 2, 2024
August 2024 Newsletter
August 1, 2024
The new MPI R01 from the NIH NHLBI, entitled “Role of Factor XII in Thrombo-Inflammatory Complications of Sickle Cell”, was awarded to Rafal Pawlinski, PhD of University of North Carolina at Chapel Hill and to Evi Stavrou, MD of Case Western Reserve University. The four-year $3,129,000 project is proposed to study the mechanism of FXII …
July 18, 2024
“Blood coagulation factor IX: structural insights impacting hemophilia B therapy” was recently accepted for publication in the journal Blood. The work is a collaboration between BRC Center member Dougald Monroe and Leiden University Medical Center investigators Rianne Elaine van Diest and Mettine H A Bos. This review focuses on analyzing the structure of factor IX …
July 8, 2024
Yohei Hisada, Ph.D. awarded SOM Boost funding award from the Dean’s office. The Dean’s Office will provide proposal Mechanisms of coagulopathy and bleeding in acute promyelocytic leukemia with Boost funding. The Boost award will provide $25,000 to help sustain his project and obtain preliminary data during the resubmission and review process of R01 grant. UNC …
July 2, 2024
The International Society on Thrombosis and Haemostasis (ISTH), an international medical and scientific professional Society advancing the understanding, prevention, diagnosis, and treatment of thrombosis and hemostasis, announces the ISTH 2024 Congress will be hosted in Bangkok, Thailand for the first time on June 22-26, 2024, at the Queen Sirikit National Convention Center. The ISTH Congress …
July 2, 2024
Melissa Caughey PhD received an NIH grant related to sickle cell disease: “Chronic dehydration in sickle cell disease: an actionable biomarker to prevent vaso-occlusive episodes” The National Institutes of Health is the largest public funder of biomedical research in the world. In fiscal year 2022, NIH invested most of its $45 billion appropriations in research …
June 10, 2024
A manuscript entitled “Disease severity drives thrombosis risk in women with sickle cell disease in a single-center retrospective study” was recently accepted in Research and Practice in Thrombosis and Haemostasias. The research was initiated by Jennifer Light, MD, during her fellowship in the UNC Pediatrics Division of Hematology and Oncology. She performed her basic research …