February 2, 2024
In the recently published work in Proceedings of the National Academy of Sciences (PNAS), Dr. Antoniak’s and Dr. Mackman’s groups from the UNC Blood Research Center show that SARS-CoV-2 encodes antimicrobial peptides (xenoAMPs) which can form proinflammatory complexes. These complexes induced a proinflammatory and procoagulant phenotype in cells in vitro and in mice in vivo. …
February 1, 2024
Read full article This paper, which was first-authored by former graduate trainee James Byrnes, investigated the relationship between coagulation factor XIII A and B subunits in circulation. Although these subunits are produced in different tissues, their data reveal a unique reciprocal regulatory mechanism in which each subunit determines the circulating half-life of the other subunit. …
January 31, 2024
Myocarditis Foundation Awards 2023 Fellowship Grant Myocarditis Foundation proudly awards 2023 Fellowship Grant to Dr. Swati Sharma of University of North Carolina, Chapel Hill One of the 2023 Fellowship Grants was awarded to Dr. Swati Sharma, for her work on: “The Protective Role of Platelet Protease-activated Receptor4 (PAR4) in Coxsackievirus (CVB3) Myocarditis”. Dr. Sharma came to …
January 17, 2024
Dr. Yohei Hisada has been appointed as an Early Career Editorial Board member of ATVB. He will serve for two years, from January 2024 to December 2025. ATVB site
January 17, 2024
View January 2024 Newsletter
January 16, 2024
Dr. Dre’Von Dobson, former graduate student in Dr. Alisa Wolberg’s laboratory received a 2024 JTH Editors Award for his paper entitled, “Novel Genetic Regulators of Fibrinogen Synthesis Identified by an In Vitro Experimental Platform” published in the Journal of Thrombosis and Haemostasis in 2023. Link to article: JTH
January 11, 2024
Paper published in Blood documenting how a nonpolymerizable fibrinogen can protect against thrombosis without compromising hemostasis. This work was featured on the cover and designated a Plenary Paper by the journal. An image of the cover is attached. Here is a link to the article: https://ashpublications.org/blood/article-abstract/143/2/105/498325/Mice-expressing-nonpolymerizable-fibrinogen-have?redirectedFrom=fulltext. The lead author on this work was Woosuk Steve Hur. …
January 9, 2024
Project Title: Evaluation of a C1 inhibitor variant as a novel hemostasis sparing anticoagulant Awardee: Ana Sachetto Mentor: Nigel Mackman Co-mentor: Steven Grover Total amount awarded: $151,564
November 16, 2023
The 17th Annual Earl W. Davie Symposium November 16, 2023 Dr. Alisa Wolberg presented a Keynote Address entitled, “Exploring the determinants of clot formation in thrombosis and bleeding” at the 2023 Earl Davie Symposium in Vancouver, BC. Website: 2023 Earl Davie Symposium
November 10, 2023
Clifford V. and Drusilla R. Harding Lecture Series: November 10, 2023 Dr. Alisa Wolberg presented the 2023 Clifford and Drusilla Harding Invited Lecture entitled, “Fibrinogen and factor XIII in thrombosis: old proteins, new functions” at Oakland University. Website: Clifford and Drusilla Harding Lecture
September 25, 2023
Harish Eswaran, MD and Stephan Moll, MD co-authored a publication in Blood Advances titled Evaluating complement dysregulation in livedoid vasculopathy using a functional assay. Livedoid vasculopathy (LV) is a chronic skin condition characterized by severely painful ulcers that come and go on the legs and feet. LV is caused by thrombosis in the small blood …
September 11, 2023
Steve Hur, PhD, is one of five recipients of the Postdoctoral Awards for Research Excellence from the UNC Office of Postdoctoral Affairs in recognition of research promise demonstrated by individual postdoctoral scholars. He will present his research during University Research Week in October.