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James Howard, MD: UCB’s Global Corporate Website press released regarding the RAISE clinical trial of zilucoplan

April 14, 2023
On April 13th, 2023, the UCB’s Global Corporate Website released a press statement regarding the RAISE clinical trial of zilucoplan – one of two drugs being reviewed for the treatment of myasthenia gravis. The trial was led by James Howard, MD, who is a neurology professor at the UNC School...

New NIH R21 award to Dr. Li-Ming Hsu, Neurology postdoc, and new R01 award to the Shih lab advance neuroimaging science

April 12, 2023
Dr. Li-Ming Hsu, a postdoctoral researcher in Ian Shih’s lab, received a new R21 award from the National Institute of Drug Abuse to study the role of anterior cingulate cortex in nicotine addiction. Dr. Ian Shih received a new R01 award from the National Institute of Neurological Disorders and Stroke with collaborators...

Shih lab members published on Nature Communications, Science Advances, and Nature Neuroscience

April 11, 2023
Researchers in the Shih lab published novel findings on causal control of the anterior insular cortex on the default mode network of the brain using selective neural stimulation (Nature Communications, featured as an Editor’s highlight article), and multi-channel optical recording of neural activity changes during fMRI (Science Advances, see also Press release, Video...

UNC MS Center Recognized as a Center for Comprehensive MS Care by the National MS Society

April 11, 2023
A prestigious recognition, the National MS Society awards this title to a handful of healthcare providers each year   Chapel Hill, NC – On March 28, 2023, UNC’s MS/Neuroimmunology Division, a leading provider of care for people living with multiple sclerosis (MS), has been officially recognized as a Center for Comprehensive...

Dr. Yen-Yu Ian Shih announced as Neurology’s Vice Chair for Research

August 12, 2022
UNC Neurology is excited to announce Dr. Yen-Yu Ian Shih as its next Vice Chair for Research. Dr. Shih has over 10 years of research experience at UNC Neurology, joining the faculty in 2012 and appointed Associate Professor in 2017. Along with his position in Neurology, Dr. Shih has also...

UNC researchers secure more than $1B in funding for third consecutive year

July 23, 2022
Research at the University of North Carolina at Chapel Hill continues to grow, bringing in more than $1.2 billion in funding awards during the 2022 fiscal year. This is the third year in a row that research awards have topped $1 billion, facilitating research projects and experiments for external sponsors like...

Shih Lab Earns NeuroImage ‘Paper of the Year’ Honors

July 7, 2022
The lab of Ian Shih, PhD, received the top prize from the journal NeuroImage for brain research featuring fMRI and fast-scan cyclic voltammetry. First author was Lindsay Walton, PhD.

Scientists Detail Brain Dynamics Implicated in Neurological Conditions

May 5, 2022
UNC School of Medicine researchers led by Ian Shih, PhD, used fMRI and a genetic mouse model to study the effects of a neurotransmitter on brain network functional connectivity, a dynamic process crucial for human health and behavior.

FDA Approves Treatment for Myasthenia Gravis After Phase III Study Led by James Howard, MD

May 5, 2022
James F. Howard, Jr, MD, in the UNC Department of Neurology is the lead primary investigator in the CHAMPION-MG trial for Ultomiris (ravulizumab-cwvz) as a treatment for adults with generalised myasthenia gravis who are anti-acetylcholine receptor antibody-positive, which represents 80% of people living with the disease.

Interim Data Suggest Long-term Treatment with VYVGART Provides Improvement in Generalized Myasthenia Gravis Disease Scores

April 7, 2022
James F. Howard Jr., MD, professor in the UNC Department of Neurology, was principal investigator of the ADAPT+ trial for the experimental drug efgartigimod, developed by Belgian pharmaceutical company Argenx.