On September 16, 2021, the Student Seminar series resumed with virtual presentations by Cathy (Anderson) Spangler and Gabby Budziszewski.
Cathy (Anderson) Spangler
Seminar title: “Exploring the mechanistic basis of nucleosome interactions”
PI: Robert McGinty
In this talk, Cathy discussed how we have recently used bulk and single-molecule biophysical and cellular studies to investigate how different interaction interfaces between histone methyltransferase Dot1L and the nucleosome contribute to Dot1L binding and activity in leukemia.
Gabby Gabby Budziszewski
Seminar title: “Chromatin kinase VRK1 engages the nucleosome multivalently to phosphorylate histone H3 threonine 3”
PI: Rob McGinty
In this talk, Gabby discussed the mechanism by which VRK1 binds the nucleosome: namely, by binding both DNA linker regions as well as the histone disk face. The multivalent nature of this interaction has implications for the kinase’s ability to phosphorylate histone H3 tails, a function that is crucial to the proper segregation of chromosomes during mitosis.
Fall 2021 and Spring 2022 BCBP Student Seminar Series talks will be held virtual via zoom.
Student seminars for students by students occur Third Thursday of every month at noon on 9/16, 10/21, and 11/18.
Student seminars for students by students occur Third Thursday of every month at noon on 1/20, 2/17, 3/17, 4/21, and the Award ceremony will be held on 5/19.
Students have opportunities to nominate their peers for awards that will be held on May 19. Students, please check your email from Odessa for the link to the nomination form.
The award categories are:
- Excellent presentation organization and clarity
- Excellent visual aids/appeal
- Ability to connect with the audience
- Excellent timing/pacing of the presentation
- Overall outstanding presentation
Reem, Rhese, and Jeff will present Student Seminars over Zoom on October 21.