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UBE2R and S image

2 weeks ago

New publication in EMBO: Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes

Conserved helix-turn-helix motif contributes differentially to #polyubiquitination in various #cellcycle E2 enzymes - via distinct donor/acceptor #ubiquitin interactions. A collaborative effort led by Kaeli Welsh (UNC Pharmacology) who is the lead author amongst the colleagues, Nick Brown (Pharmacology) and Joe Harrison (a former postdoc in Kuhlman lab) and in BCBP (Josh Boyer, Brenda Temple, Derek Bolhuis, Qi Zhang) and other colleagues.