Meet Dr. Shawn Yu

Hello, my name is Shawn Yu. I am a second-year clinical fellow in Hematology and Oncology and a new postdoctoral fellow in Clinical Pharmacology working with Dr. Brian Kuhlman and Dr. William Kim. I am working to design multispecific T-cell engagers targeting cancer-testis antigens to treat solid tumors such as urothelial carcinoma of the bladder.
Before arriving at UNC, I studied Chemical Engineering at the California Institute of Technology as an undergrad. Later, I pursued my M.D./Ph.D. at the University of Washington. During my graduate research, I helped develop a computationally designed de novo, hyperstable mimic of interleukin-2/15 which lacked a CD25 interaction surface, which demonstrated antitumor effects in mouse models of cancer. Subsequently, I completed medical residency in internal medicine at the University of Southern California before arriving at UNC for fellowship. I am thrilled to have the opportunity to resume my research career in a project that combines my scientific and clinical interests.
Beyond science and medicine, I love classic animation and enjoy many sports including football, basketball, and track. I’m excited to meet everyone in the department, and I appreciate the warm welcome!