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Chief Clinical Officer, UNC Health | President, UNC Physicians | Van L. Weatherspoon, Jr. Eminent Distinguished Professor


New Patients/Referrals: 984-974-4175
Returns/Follow-up Appointments:  (984) 974-0000

Dr. Matthew Ewend is the Chief Clinical Officer of UNC Health & President of UNC Physicians and former Chair of the Department of Neurosurgery. He joined the faculty in 1997 after completing medical school, neurosurgery residency, and a brain tumor fellowship at The Johns Hopkins School of Medicine. Dr. Ewend’s clinical interests center on endoscopic and minimally invasive treatment of brain tumors, especially pituitary tumors, skull base tumors, and metastases.

In addition, he oversees the quality program, the value program, and the partnership of UNC Physicians with our hospitals. His research interests are in novel imaging of the brain, treatment of brain metastases, and outcomes for endoscopic neurosurgery.

When asked about his goals for a new patient visit, Dr. Ewend says, “My first goal is to build a strong relationship with my patient and his or her family. In addition to a thoughtful review of their case, patients can expect an understandable explanation of their condition, discussion of all the treatment options, and my opinion as to which option(s) might be best. At UNC, we work in teams to bring you the best care. If needed, I will help you to assemble this team. I pride myself on making the issues of neurosurgery easy to understand for my patients. After all, it isn’t really rocket science. I look forward to meeting you.”

Dr. Ewend has been named to the 2021 Best Doctors in America® list.

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  • Van L. Weatherspoon, Jr. Eminent Distinguished Professor, Department of Neurosurgery
  • Chief Clinical Officer, UNC Health
  • President, UNC Physicians

Brain tumors, pituitary tumors, endoscopic surgery, metastatic tumors, CyberKnife®, skull base surgery and hydrocephalus.

Fellowship – Neuro-Oncology; The Johns Hopkins Hospital, 1994-1996
Residency – Neurosurgery; The Johns Hopkins Hospital, 1991-1997
Internship – Surgery; The Johns Hopkins Hospital, 1990-1991
M.D. – Medicine; Johns Hopkins University School of Medicine, 1990
B.A. – Mathematics, Health Sciences; Kalamazoo College, 1986

Neurological Surgery – Board Certified, 2001

For recent publications, please visit Dr. Matt Ewend’s PubMed listing.

  • Phone Number

    984-974-4175 (Office Phone)

  • Address

    Physicians Office Building

    170 Manning Drive, CB# 7060

    Chapel Hill, NC 27599