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text "Welcome to the UNC Program in Chromatin and Epigenetics Epigenetic regulation is recognized to play a fundamental role in cell growth, cell fate and organismal development. While playing a key role in regulating our genome, much of the epigenetic machinery is found to be recurrently mutant and/or de-regulated in many human diseases including cancer. At UNC, our mission is to address the fundamental gaps in knowledge surrounding epigenetic regulation, with a long-term goal of developing novel therapeutic approaches towards treating human disease. The Chromatin and Epigenetics Research Program Our program is centered on a highly collaborative and team science environment that has a dedicated goal of solving fundamental and challenging problems in chromatin biology – with an emphasis on developing novel approaches towards treating human disease. With the large number of research faculty at UNC specializing in different areas of epigenetic research, we are optimally positioned to meet this challenge. Faculty at UNC are focused on i) the basic mechanisms of epigenetic regulation using a variety of model organisms, ii) high-throughput drug discovery efforts to"


Dr. Brian Strahl 2024
Brian Strahl, PhD
Co-Director, Program in Chromatin and Epigenetics

The UNC Program in Chromatin and Epigenetics is dedicated to enhancing the epigenetics community and advancing our understanding of epigenetic regulation, a key driver of cellular growth, development, and diseases like cancer. The program aims to bring the epigenetics community together to inspire collaboration and to help faculty and trainees bridge critical knowledge gaps. With over 40 faculty and labs, including partnerships with NIEHS, the program drives innovation in fundamental mechanisms, drug discovery, and clinical research using cutting-edge technologies. It provides world-class training for students and postdoctoral researchers, recently launching a new Certificate Program for PhD-earning students, resulting in the creation of two new advanced 3 courses. The program is supported by a monthly seminar series (Carolina Chromatin Consortium (C3)) and a yearly symposium, funded by Lineberger, biochemistry & biophysics, pharmacy, genetics, Biology, and iBGS. With diverse funding sources and faculty, the program fosters collaboration and drives innovative research to advance the field.

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