Jeff Bonin successfully defended his dissertation on April 19th, 2022, and received his Ph.D. The dissertation, titled “Dynamic Allostery in Substrate Binding by Human Thymidylate Synthase”, was completed under the direction of Dr. Andrew Lee.
Jeff received a B.A. in physics with a minor in bioinformatics from Washington University in St. Louis in 2016. At Washington University, Jeff participated in research efforts in a number of different fields, including radiology, astrophysics, and metabolic engineering.
In 2017, Jeff joined the Biochemistry and Biophysics department following the biophysics track. His research in Dr. Andrew Lee’s group focused on using nuclear magnetic resonance (NMR) spectroscopy methods to characterize the dynamics of the enzyme human thymidylate synthase in order to understand the mechanism of substrate binding cooperativity in this protein.
After finishing up at UNC, Jeff plans to join Dr. Lewis Kay’s group at the University of Toronto, where he will continue to use NMR spectroscopy to study the role of dynamics in the function of large proteins.
Publications on PubMed: Bonin JP