The Pagano Award was established in 2002 to honor outstanding papers by postdoctoral fellows who are first authors of these papers. Winners are selected through a competitive process and are honored for their authorship of articles in high-impact journals.
The paper authored by Scott Rothbart, PhD, is “Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation” published in Nature Structural & Molecular Biology. Dr. Rothbart’s paper explores how a protein called UHRF1 “reads” the histone code in a specific way to perform an important cellular function.
Dr. Rothbart is currently a postdoctoral fellow training in the lab of Dr. Brian Strahl, associate professor of Biochemistry and Biophysics. Dr. Rothbart's research focuses on the regulation of chromatin-templated biological processes by the 'histone code'. Particularly, he is interested in the biochemistry and biology of a chromatin-interacting protein, UHRF1, as a bridging molecule at the interface of histone post-translational modifications and DNA methylation.
Learn more about the other recipients here: http://unclineberger.org/news/unc-lineberger-announces-2013-joseph-s-pagano-awards