postdoc Dr. Yanqiong Zhang in Liu lab, Dr. Zhe Ma in Damania lab and a BBSP student Ying Wang

1 month ago

Liu and Damania Labs identified new proteins controlling cGAS activation

Hyperactivation of innate immunity results in autoimmune diseases, while deficiency in innate immunity is prone to tumorigenesis. Thus, the activity of innate immune signaling is tightly controlled but the regulatory mechanisms have not been fully elucidated. Recently, the labs of Liu and Damania published a study in iScience revealing a role of the bacterial protein streptavidin in binding and facilitating cGAS activation.

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