5 years ago
Congratulations to graduate student Odessa Goudy in the Brian Kuhlman lab for making it to the Three Minute Thesis (3MT) finals! As part of the UNC Research Week, the Finals will be live streamed on October 21, 2000 at 7 pm. Please cheer on Odessa virtually on Wednesday night.
5 years ago
Cathy Spangler published a paper in collaboration with Joshua Boyer, Joshua Strauss, Andrew Cesmat, Pengda Liu, Robert McGinty, and Qi Zhang, titled "Structural basis of nucleosome-dependent cGAS inhibition."
5 years ago
Led by Qi Zhang, PhD, and Robert McGinty, MD, PhD, UNC-Chapel Hill scientists used cryo-electron microscopy technology to produce the first-ever high-resolution structure of the protein cGAS bound to the DNA packaging unit inside human cell nuclei, revealing how cGAS responds to foreign or damaged DNA, but not the body’s healthy DNA.
5 years ago
Carolina also ranked in the top 20 for 11 academic subject areas according to the 2020 Academic Ranking of World Universities released by the Shanghai Ranking Consultancy on August 15.
5 years ago
Hyperactivation of innate immunity results in autoimmune diseases, while deficiency in innate immunity is prone to tumorigenesis. Thus, the activity of innate immune signaling is tightly controlled but the regulatory mechanisms have not been fully elucidated. Recently, the labs of Liu and Damania published a study in iScience revealing a role of the bacterial protein streptavidin in binding and facilitating cGAS activation.
5 years ago
It is known that the three-dimensional organization of the genome within the nucleus is important for proper gene expression and ultimately development. The mechanisms behind this organization, however, are not yet fully understood. Recently, the lab of Jill Dowen, PhD, published a study in Epigenetics & Chromatin solving a piece of this complex puzzle.
5 years ago
Carolina is pausing all undergraduate instruction on Aug. 24 and Aug. 25 to help students catch their breath and make the transition to remote learning. Undergraduate classes will resume Aug. 26
5 years ago
Gabrielle Dardis, a BCBP graduate student in Albert Baldwin’s lab (Lineberger Comprehensive Cancer Center), was awarded the Ruth L. Kirschstein NRSA Predoctoral Fellowship.
5 years ago
Effective Wednesday, August 19, all undergraduate in-person instruction will shift to remote learning. Courses in our graduate, professional and health affairs schools will continue to be taught as they are, or as directed by the schools. Academic advising and academic support services will be available online. Our research enterprise will remain unchanged.
5 years ago
Nicole Arruda (Jill Dowen lab) published a paper titled “Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells” in Epigenetics and Chromatin (DOI:10.1186/s13072-020-00353-9). GMB student Megan Justice is a co-author. Image: Heatmaps of expression changes in Stag1 and Stag2 mutant cells and of STAG1 and STAG2 ChIP-seq; see article for details). August 10, 2020 Arruda, …
5 years ago
Congratulations to Jean Marie Mwiza, a graduate research assistant in Dr. Bergmeier’s Lab, for earning a Ruth L. Kirschstein Predoctoral Fellowship for his project, "Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis"!
5 years ago
Cathy Anderson, a BCBP graduate student and a member of Rob McGinty's lab, has been awarded an NCI Predoctoral to Postdoctoral Fellow Transition Award.
