Health Outcomes of Discontinuing Aspirin in Older Adults with ADRD

Project: Health Outcomes of Discontinuing Aspirin in Older Adults with Alzheimer’s Disease and Related Dementias

Grant Number: R01AG079219-01A1 (National Institutes on Aging)

Evidence is lacking to guide patient-centered decision-making about aspirin for older adults with AD/ADRD. Although the benefits of aspirin for cardiovascular prevention have been well documented in the literature, there is limited evidence for adults with advanced age, frailty, and AD/ADRD, for whom the risk of bleeding may outweigh the potential benefits. Led by Dr. Carolyn Thorpe, this study will use real-world healthcare data to examine patterns, benefits, and harms of discontinuing aspirin in older nursing home residents with ADRD.

Role

Co-Investigator

Key Collaborators

Carolyn Thorpe (PI)