molecular analysis of neuronal migration and layer formation in cerebral cortex

hormone/paracrine/autocrine regulation of the renal microcirculation, calcium signaling in vascular smooth muscle cells, pathophysiology of hypertension

James Bear, PhD

molecule-based and unbiased genetic/proteomic approaches to understanding cell migration and other aspects of actin-based motility

Con Beckers, PhD

toxoplasma gondii cell biology: essential signaling pathways in the parasite and the structure, assembly, and function of its membrane skeleton

Jay Brenman, PhD

genetic models and signaling relevant to metabolic disease and type 2 diabetes

Patrick Brennwald, PhD

Interim Department Co-Chair
cell polarity and vesicle transport in eukaryotic cells

Keith Burridge, PhD

Signaling that occurs downstream from integrin-mediated focal adhesions and cadherin-mediated cell-cell adhesions; understanding Rho family GTPases; mechanotransduction; leukocyte transendothelial migration

Kathleen Caron, PhD

genetically engineered animal models in study of human disease

Richard Cheney, PhD

motor proteins, cytoskeleton, and cell motility

M. Joseph Costello, PhD

intercellular junctions between fibers in normal and cataractous lenses using light and electron microscopy

Douglas Cyr, PhD

Director of Graduate Studies - Cell and Developmental Biology
chaperone assisted protein folding and degradation in eukaryotic cells; defective protein folding in cystic fibrosis and neurodegeneration

Mohanish Deshmukh, PhD

regulation of cell survival and death with a focus on apoptosis pathways in neurons, stem cells and cancer

Andrew Dudley, PhD

tumor microenvironment, tumor angiogenesis, vascular stem cells

James Faber, PhD

physiologic and genetic regulation of collaterogenesis during development and in ischemic disease; vascular growth and remodeling

Kurt Gilliland, PhD

the development of the human lens and the disease cataract

Michael Goy, PhD

a novel endocrine peptide that coordinates electrolyte transport in the gut and the kidney; Feedback regulation by nitric oxide in a simple neuronal circuit

Stephanie Gupton, PhD

coordination and regulation of cytoskeletal dynamics and membrane trafficking that underlie cell shape change and cell motility during development and cancer metastasis

Scott Hammond, PhD

biochemical and biological pathways of non-coding RNAs

Kenneth Jacobson, PhD

membrane dynamics: the study of lipid rafts in model and biomembranes using new biophysical techniques for light microscopy

Edward Kernick, DPM

human anatomy and neuroanatomy; central nervous system and motor control of limb muscles

P. Kay Lund, PhD

Insulin, IGFs, obesity and gastrointestinal disease; normal and cancer associated intestinal stem cells; fibrosis in inflammatory bowel diseases; aging and stem cells

Ben Major, PhD

Proteomic and functional genomic analysis of signal transduction.  Protein interaction networks, computational biology, mass spectrometry, WNT signaling, KEAP1-NRF2, lung cancer.

Deborah O'Brien, PhD

sperm metabolism and motility, genetics of male infertility, structure-based drug design for male contraception

Michael O'Rand, PhD

characterization of sperm molecules; targets for infertility diagnosis and contraception

Carol Otey, PhD

Interim Department Co-Chair
cell motility in embryonic development, wound-healing and cancer metastasis

Peter Petrusz, MD, PhD

effects of hormones on brain and reproductive system

Ben Philpot, PhD

Angelman syndrome; Rett syndrome; autism spectrum disorders; neurodevelopmental disorders; experience-dependent synaptic plasticity; restoration of plasticity in neurological disorders

Scott Randell, PhD

airway epithelial biology—stem cells, host defense, and response to injury

John Rawls, PhD

intestinal microbiota, digestive physiology, adipose tissue physiology, zebrafish

John Reader, DPhil

protein translation apparatus with a particular focus on aminoacyl-tRNA synthetases and tRNAs

Lola Reid, PhD

growth and differentiation of stem cells

Aldo Rustioni, MD

glutamate receptors and an understanding of how different subunits of the receptors may contribute to define the quality of somesthesic stimulus

Robert Sealock, PhD

cell biology of the neuromuscular junction and of dystrophin-associated proteins

Spencer Smith, PhD

neuroscience and neuroengineering

Kathleen Sulik, PhD

pathogenesis and mechanisms underlying birth defects induced by environmental and genetic factors

Robert Tarran, PhD

signal transduction and the regulation of ion transport in airway epithelia

Eleni Tzima, PhD

Director of Graduate Studies - Cell and Molecular Physiology
mechanisms of vascular endothelial cell signaling and angiogenesis in response to hemodynamic stimuli

Ellen Weiss, PhD

visual signaling in the vertebrate retina; photoreceptor cells and mechanisms of light adaptation

Mark Zylka, PhD

molecules and mechanisms for pain; Angelman Syndrome therapies