14 years ago
Dokholyan lab has a cover story in the December 7, 2011 issue of Structure. Dagliyan et al. present a rapid molecular dynamics-based approach to reveal the mechanism of protein-peptide recognition. The authors find that the peptide, rather than the protein, undergoes an induced fit, and that electrostatic interactions guide the peptide toward the binding region.
14 years ago
Congratulations to Dr. Julia Brittain, Research Assistant Professor of Biochemistry & Biophysics, who was recently selected to the Editorial Board for the publication World Journal of Hematology.
15 years ago
Congratulations to Dr. Henrik Dohlman, Professor & Vice-Chair of Biochemistry & Biophysics, who was elected as a 2011 AAAS fellow.
15 years ago
Exposure to UV radiation triggers DNA lesions that can lead to skin cancer, the most common type of cancer in the United States. Previous studies in mice have shown that levels of a protein called XPA, involved in repairing UV-induced DNA lesions, waxes and wanes with the time of day. Shobhan Gaddameedhi et al. found that the protein's level and activity in mouse skin cells are at their lowest at 4 AM and their highest at 4PM.
15 years ago
Nuri Ozturk, postdoctoral fellow working in the laboratory of Aziz Sancar in the Department of Biochemistry & Biophysics receives a 2011 Postdoctoral Research Excellence Award.
15 years ago
Shobhan is a postdoctoral fellow working in the laboratory of Aziz Sancar in the Department of Biochemistry & Biophysics. His project "Role of the Circadian Clock in UV-Induced Skin Carcinogenesis" was the only CEHS Pilot Project to be funded by a postdoctoral researcher!
15 years ago
The University of North Carolina at Chapel Hill, Washington University School of Medicine in St. Louis, and Boise State University have been named partners in one of five US centers that will use genetic data to search for proteins that are abnormally made by cancer cells. The partnerships form the new Clinical Proteomic Tumor Analysis Consortium (CPTAC) supported by the National Cancer Institute (NCI).
15 years ago
Making Translational Research Tangible - At the University of North Carolina, Chapel Hill (UNC), students are being encouraged to think like they're in charge -- and then to take charge. Some of these enterprising students are making the transition from trainee to entrepreneur as they complete their doctoral degree.
15 years ago
“I believe Jin has a great future in cancer biology and his research is likely to have an immediate impact on the health and welfare of the people of North Carolina,” said Aziz Sancar, M.D., Ph.D., Lee's dissertation adviser. Jin is currently a graduate student in the Department of Biochemistry & Biophysics.
15 years ago
On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism's physiology and behavior.
15 years ago
Finding published in the July 21, 2011 issue of Science shows that researchers from the UNC School of Medicine have discovered the seventh and eighth bases of DNA.
15 years ago
This award, established by the Board of Govenors in 1997, acknowledges a lifetime of contributions to a broad range of teaching and learning, particularly mentoring beyond the classroom.