5 years ago
After completing his PhD degree studying transcriptional kinases in yeast, Pengda Liu had one goal for his career: to make a difference for human health. Today, he is on the cusp of advancing a promising compound into the drug discovery and development pipeline. If successful, it would become the first targeted treatment for patients with …
5 years ago
Hyperactivation of innate immunity results in autoimmune diseases, while deficiency in innate immunity is prone to tumorigenesis. Thus, the activity of innate immune signaling is tightly controlled but the regulatory mechanisms have not been fully elucidated. Recently, the labs of Liu and Damania published a study in iScience revealing a role of the bacterial protein streptavidin in binding and facilitating cGAS activation.
5 years ago
It is known that the three-dimensional organization of the genome within the nucleus is important for proper gene expression and ultimately development. The mechanisms behind this organization, however, are not yet fully understood. Recently, the lab of Jill Dowen, PhD, published a study in Epigenetics & Chromatin solving a piece of this complex puzzle.
5 years ago
Carolina is pausing all undergraduate instruction on Aug. 24 and Aug. 25 to help students catch their breath and make the transition to remote learning. Undergraduate classes will resume Aug. 26
5 years ago
Cassandra Hayne (2017) shares two publications one on SARS-COV-2 and one breakthrough article in Nucleic Acids Research journal.
5 years ago
Gabrielle Dardis, a BCBP graduate student in Albert Baldwin’s lab (Lineberger Comprehensive Cancer Center), was awarded the Ruth L. Kirschstein NRSA Predoctoral Fellowship.
5 years ago
Effective Wednesday, August 19, all undergraduate in-person instruction will shift to remote learning. Courses in our graduate, professional and health affairs schools will continue to be taught as they are, or as directed by the schools. Academic advising and academic support services will be available online. Our research enterprise will remain unchanged.
5 years ago
Nicole Arruda (Jill Dowen lab) published a paper titled “Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells” in Epigenetics and Chromatin (DOI:10.1186/s13072-020-00353-9). GMB student Megan Justice is a co-author. Image: Heatmaps of expression changes in Stag1 and Stag2 mutant cells and of STAG1 and STAG2 ChIP-seq; see article for details). August 10, 2020 Arruda, …
5 years ago
Liu lab received a NCI R01 grant to investigate novel function of cGAS in modulating breast cancer pathology. This five year grant will enable Liu lab to continue their current journey in investigation roles of innate immunity signaling in cancer.
5 years ago
Congratulations to Jean Marie Mwiza, a graduate research assistant in Dr. Bergmeier’s Lab, for earning a Ruth L. Kirschstein Predoctoral Fellowship for his project, "Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis"!
5 years ago
The National Institute of Dental and Craniofacial Research has awarded a five-year, $3.78 million grant to a team of UNC researchers to study to whether experimental tumor and blood tests can accurately detect HPV-linked head and neck cancer, predict if the cancer will respond to treatment, and identify which cancer will recur.
5 years ago
Cathy Anderson, a BCBP graduate student and a member of Rob McGinty's lab, has been awarded an NCI Predoctoral to Postdoctoral Fellow Transition Award.
