Skip to main content
  • Associate Professor of Pediatrics and Neurology – Child Neurology, Neurodevelopmental Disabilities
  • Carolina Institute of Developmental Disabilities (CIDD)

I am a neurodevelopmental neurologist with a clinical and research focus on neurodevelopmental conditions across the lifespan. I am developing a multi-disciplinary, comprehensive program of translational research around detection (particularly early detection) and multi-modal interventions (including pharmacotherapeutics, cognitive-behavioral therapies, and community support and services).

I have great interest in expanding complementary pre-clinical studies relevant to developing therapeutics for rare neurogenetic neurodevelopmental disorders (NDDs) across multiple levels of analysis and across multiple conditions throughout the lifespan, realizing that the developmental framework is a lifetime perspective. Individuals born with NDDs are at increased risk for conditions later in life. Whether occurring early (as in NDDs) or late (as in NDGDs), I am interested in studying the cascade of factors over the course of development that lead to disorders of the brain.

I am currently leading several clinical trials in Angelman syndrome, Fragile X syndrome, and Tuberous Sclerosis Complex through the Carolina Institute for Developmental Disabilities in collaboration with the Department of Neurology and UNC Neuroscience Center.

Clinically, I diagnose and treat a variety of neurodevelopmental and neurogenetic conditions in children and adults.

Clinical Interests

  • Children and adults with tuberous sclerosis complex (all aspects of TSC including a separate TSC-associated Neuropsychiatric Disorders [TAND] Clinic at the CIDD)
  • Neurofibromatosis Type 1
  • Children and adults with autism spectrum disorders and associated conditions (e.g. seizures, behavior)
  • Neurogenetic conditions including but not limited to Angelman syndrome, Fragile X syndrome, Down syndrome, Dup 15q, and others
  • Behavioral challenges associated with neurodevelopmental conditions


  • Board Certified in Pediatrics, 2011
  • Board Certified in Neurology with Special Qualification in Child Neurology, 2012
  • Board Certified in Neurodevelopmental Disabilities, 2013


  • Doctor of Medicine (MD)
    Albany Medical College, 2006
  • Bachelor of Arts, Biology with Honors, Magna cum laude
    Ithaca College, 2002
  • Combined Residency in Child Neurology and Neurodevelopmental Disabilities
    Cincinnati Children’s Hospital Medical Center, 2006-2012
  • Residency in Pediatrics
    Cincinnati Children’s Hospital Medical Center, 2006-2008


Jamie Capal, MD
  • Addresses

    Carolina Institute for Developmental Disabilities

    101 Renee Lynne Court

    Carrboro, NC 27510
  • UNC Hospitals Child Neurology Clinic at Carolina Pointe II, Chapel Hill

    6011 Farrington Road, Suite 100

    Chapel Hill, NC 27517