postdoc Dr. Yanqiong Zhang in Liu lab, Dr. Zhe Ma in Damania lab and a BBSP student Ying Wang

Hyperactivation of innate immunity results in autoimmune diseases, while deficiency in innate immunity is prone to tumorigenesis. Thus, the activity of innate immune signaling is tightly controlled but the regulatory mechanisms have not been fully elucidated. Recently, the labs of Liu and Damania published a study in iScience revealing a role of the bacterial protein streptavidin in binding and facilitating cGAS activation.

UNC graduate students Alexis Stutzman (Dowen lab) and Markia Smith start a movement.

It is known that the three-dimensional organization of the genome within the nucleus is important for proper gene expression and ultimately development. The mechanisms behind this organization, however, are not yet fully understood. Recently, the lab of Jill Dowen, PhD, published a study in Epigenetics & Chromatin solving a piece of this complex puzzle.

Carolina is pausing all undergraduate instruction on Aug. 24 and Aug. 25 to help students catch their breath and make the transition to remote learning. Undergraduate classes will resume Aug. 26

Cassandra Hayne (2017) shares two publications one on SARS-COV-2 and one breakthrough article in Nucleic Acids Research journal.

Important information regarding COVID testing at UNC.

Gabrielle Dardis, a BCBP graduate student in Albert Baldwin’s lab (Lineberger Comprehensive Cancer Center), was awarded the Ruth L. Kirschstein NRSA Predoctoral Fellowship.

This week, August 17-21, 2020, follow #BlackInGeneticsWeek on Twitter. Founded by Alexis Stutzman @stutzman_alexis GMB graduate student in Jill Dowen and Dan McKay labs.

Effective Wednesday, August 19, all undergraduate in-person instruction will shift to remote learning. Courses in our graduate, professional and health affairs schools will continue to be taught as they are, or as directed by the schools. Academic advising and academic support services will be available online. Our research enterprise will remain unchanged.

Clustered heatmaps displaying STAG1, STAG2, RAD21, and CTCF signal (Z-score normalized) at a union list of STAG1 and STAG2 peaks.

Nicole Arruda (Jill Dowen lab) published a paper titled “Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells” in Epigenetics and Chromatin (DOI:10.1186/s13072-020-00353-9). GMB student Megan Justice is a co-author. Image: Heatmaps of expression changes in Stag1 and Stag2 mutant cells and of STAG1 and STAG2 ChIP-seq; see article for details). August 10, 2020 Arruda, …

Liu lab received a NCI R01 grant to investigate novel function of cGAS in modulating breast cancer pathology. This five year grant will enable Liu lab to continue their current journey in investigation roles of innate immunity signaling in cancer.

Congratulations to Jean Marie Mwiza, a graduate research assistant in Dr. Bergmeier’s Lab, for earning a Ruth L. Kirschstein Predoctoral Fellowship for his project, "Determining the Platelet Signaling Pathway(s) Critical in Venous Thrombosis Pathogenesis"!

Tag: News 2020

Liu and Damania Labs identified new proteins controlling cGAS activation

#BlackinGenetics Attracts National Attention

Dowen lab untangles another part of the 3D genome

University leaders announce important academic updates

Cassandra K. Hayne’s 2 recent publications: SARS-COV-2 and NAR paper

COVID Testing Guidance

Graduate Student Gabrielle Dardis awarded NCI F31

Alexis Stutzman graduate student in Dowen lab founds #BlackInGeneticsWeek

Carolina Chancellor Kevin M. Guskiewicz Updates the Roadmap August 17

Nicole Arruda in Dowen lab publishes paper in Epigenetics and Chromatin

Liu Lab receives a NCI R01 grant

Jean Marie Mwiza receives a Ruth L. Kirschstein Predoctoral Fellowship