Associate Professor, Department of Pediatrics
Pediatric Neuro-Oncology Research
The Hingtgen Lab at the UNC Medical Center focuses on brain tumor research, and specifically on pediatric brain tumor research.
If you are interested in enrolling your child in a clinical trial at the UNC Medical Center, you can find a list of current clinical trials on the Children’s Oncology Group website, and the Sunshine Project’s website.
Dr. David Kram currently serves as Vice Chair of the Children’s Oncology Group New International Phase 3 Trial for Medulloblastoma. He also serves on the Advisory Council of Gift From a Child, a non-profit aimed at increasing post-mortem pediatric brain tissue donations for research. He is a translational researcher and clinical trialist. His primary research interests are in better elucidating the complex mechanisms of oncogenesis, invasion, and immune escape in low- and high-grade pediatric brain tumors, which together are now the leading cause of cancer-related death in children. His ultimate goal is to develop new therapeutic strategies for pediatric brain tumors that are more effective and less toxic.
UNC Lineberger Comprehensive Cancer Center
UNC is one of the top ten universities nationwide to receive NIH (National Institutes of Health) research funds. Cancer research, including clinical trials for pediatric tumors and neurological disorders, is conducted at the UNC Lineberger Comprehensive Cancer Center.
The Center received NCI-designation (National Cancer Institute) in 1975, becoming a comprehensive cancer center in 1990. UNC Lineberger is the only public comprehensive cancer center in the state of North Carolina. In 2016, US News and World Report ranked Lineberger as first in North Carolina and in the top 20 of all cancer centers in the nation.
UNC Lineberger’s research spans the spectrum from the laboratory to the bedside to the community as UNC faculty work to understand the causes of cancer at the genetic and environmental levels, conduct groundbreaking laboratory research, and translate findings into innovative clinical trials.